Sparse modeling of interactions enables fast detection of genome-wide epistasis in biobank-scale studies.
Published in American Journal of Human Genetics, 2025
The R implementation for this method is now available on CRAN. The full documentation is available as Github pages: SME documentation.
Recommended citation: J. Stamp, S. Pattillo Smith, D. Weinreich, L. Crawford (2025). Sparse modeling of interactions enables fast detection of genome-wide epistasis in biobank-scale studies. AJHG; doi: 10.1016/j.ajhg.2025.07.004
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